Endocrine Abstracts

Introduction: Diabetes mellitus (DM) is the most common endocrine disorder. The skin manifestations of diabetes can vary depending on the duration of the disease and the control of blood glucose levels. Almost all patients with DM eventually develop skin changes due to the long-term effects of hyperglycemia on microcirculation and skin collagen. This study was conducted to find the hospital based prevalence of mucocutaneous manifestations in patients with diabetes mellitus, th...

Introduction: Obesity is one of the major public health issues worldwide and is known to be associated with an increased risk of severe metabolic and cardiovascular complication. The aim of our study was to assess the impact of obesity severity on the metabolic profile of obese patients.Materials and methods: Cross-sectional descriptive study involving 68 obese patients carried within the National Institute of Nutrition in Tunis. The patients were divide...

Introduction: Olive oil is the most representative food of the traditional Mediterranean Diet (MedDiet) that, besides having high-monounsaturated fatty acids content, contains other minor components with biological properties. Olive oil as a food, and the MedDiet as a food pattern are associated with a decreased risk of cardiovascular disease, obesity and diabetes mellitus. The aim of this study was to determine the relationship between adherence to the Mediterranean Diet and ...

Introduction: The progressive increase in diabetes is likely to increase the incidence of amputations. Despite a wealth of research highlighting the importance of early detection and management, prevention practices remain poor, with inconsistent patient follow-up and compliance. The aim of our study was to assess the prevalence and risk factors for lower limb amputation in a third-line hospital among diabetics.Methods: It was a retrospective study inclu...

Introduction: Obesity is a major health problem through its numerous complications especially metabolic complications associated with cardiovascular risk. The aim of our work was to describe the clinico-metabolic profile of obese Tunisian adults.Methods: This was a descriptive cross-sectional study involved 174 obese patients who consulted between July and December 2020 at the Obesity Unit of the National Institute of Nutrition in Tunis. ResultsThe avera...

Introduction: Type 2 diabetes is a chronic, silent disease. Patients with diabetes could experience complications during the evolution of their disease. We studied the presence of degenerative complications during the initiation of insulin.Methods: Cross-sectional study including a group of patients with type 2 diabetes requiring a switch to insulin, hospitalized at the A department of Diabetology and Nutrition in the National Institute of Nutrition of T...

Objective: Our objective was to determine the relationship between mean blood gamma-GT (GGT) levels and chronic complications of type 2 diabetes.Patients and Methods: This was a descriptive study including 89 diabetic patients followed at the department A of the National Institute of Nutrition in Tunis.Results: The mean age was 56.44 ±13.02 years. The mean GGT level was 54.77±61.13 IU/l. Diabetes was uncontrolled in 93% of ca...

Background: Alteration of gut microbiota leads to increased intestinal permeability, inflammation, and metabolic disorders. The aim of our study was to determine the effect of prebiotic supplementation on glycemic parameters in addition to a weight loss program.Methods: This is an interventional study including 30 obese patients consulting the obesity unit of the Institute of Nutrition in Tunis. The patients were divided into 2 groups matched for age, se...

Background: Sleep is crucial for brain function, productivity, physical and mental well-being. The objective of our work was to examine the relationship between short sleep duration and its associated factors (sociodemographic characteristics, mental health and chronic diseases) in adult individuals with obesity.Methods: Cross sectional study, including 100 obese adult patients consulting the Obesity Unit of the National Institute of Nutrition in Tunis i...

Background: Obese population is at risk of psychological complications such as anxiety and depression. We carried out this study to assess the effect of a weight loss program and prebiotic supplementation on anxiety symptoms and stress levels in an obese adult population.Methods: Interventional study involving 30 obese patients consulting the obesity unit of the National Institute of Nutrition in Tunis between June and August 2022. Patients were divided ...